Stage 3 CKD Care
Approximately 15–33% of kidney function remains.Stage 3 requires supplements, renal diet, subcutaneous fluids, electrolyte balance, and management of complications.
Supplements
A combination of multiple supplements and prescription medications are required.
✔ Core Supplement Set
- Dr. Toru Protocol – AIM-based, supports kidney waste clearance
- Intensive Protocol – cellular energy, AMPK activation, antioxidant support
- Probiotics Protocol – uremic toxin reduction, gut health support
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AIM-Based Support
Dr. Toru Protocol
Regular price US$46.60Regular priceUnit price per -
AIM. AMPK. Relief.
Full Spectrum Care Set
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Toxin Burden Relief
Probiotics Protocol
2 Month Supply
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AMPK Cell Support
Intensive Protocol
2 Month Supply
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✔ Recommended Additional Supplements
- Omega-3 (EPA/DHA, 100 mg/day) – inflammation control, improved renal blood flow
- Melatonin (1 mg/day) – supports anemia prevention
✔ Veterinary Prescription Medications
- Phosphate binders (e.g., Sevelamer, Lanthanum) – bind and remove excess phosphorus
- Uremic toxin binders (e.g., activated charcoal) – absorb and eliminate toxins
Diet
Only renal prescription diets should be given.
✔ Assisted Feeding
- Self-feeding often becomes difficult in Stage 3.
- Rather than waiting and risking further deterioration, early assisted feeding is strongly recommended.
✔ Methods of Assisted Feeding
- Drop small kibbles of renal dry food into the cat’s mouth with the head tilted upward, allowing gravity to guide ingestion (most recommended)
- Blend renal wet food and feed using a syringe (※ Be careful to avoid aspiration)
※ Appetite stimulants (e.g., Mirtazapine) may be effective short term, but prolonged use can cause agitation and place strain on the heart and blood pressure—use with caution.
Subcutaneous Fluids (Sub-Q)
Daily subcutaneous fluid administration is required under veterinary supervision.
※ Caution is needed if the cat has heart or lung conditions.
✔ Dosage guideline:
- 40–50 ml(1.35–1.7 fl oz) per 1 kg(2.2 lb) of body weight per day
- Example: 4 kg (9 lb) cat → 160–200 ml/day (5.4–6.8 fl oz/day)
✔ Commonly used fluids:
- Hartmann’s Solution
- Normal Saline (NaCl 0.9%)
- Plasma-Lyte
Electrolytes
In Stage 3, blood tests should monitor and manage the following:
Phosphorus (P), Potassium (K⁺), Calcium (Ca²⁺), Bicarbonate (HCO₃⁻), Sodium (Na⁺)
✔ Elevated P – Hyperphosphatemia
- Common in Stage 3 CKD.
- Administer phosphate binders with food.
→ e.g., Sevelamer, Lanthanum
✔ Low HCO₃⁻ – Metabolic Acidosis
- Blood pH becomes acidic, disrupting electrolyte balance.
- Supplement with Sodium Bicarbonate
→ Helps alkalize blood and stabilize electrolytes
✔ Elevated K⁺ or Ca²⁺ – Hyperkalemia / Hypercalcemia
- Often occurs with persistent low HCO₃⁻ and acidosis.
→ Correct with Sodium Bicarbonate supplementation
✔ Low K⁺ – Hypokalemia
- Caused by excessive urinary potassium loss.
- Supplement with potassium products
→ e.g., Potassium Gluconate, Potassium Citrate
✔ High Na⁺ – Hypernatremia
- Adjust by switching to low-sodium fluids.
→ Replace NaCl 0.9% with Hartmann’s Solution (Lactated Ringer’s)
Kidney Checkpoints
Complications such as anemia, hypertension, and HCM (hypertrophic cardiomyopathy) may develop. During veterinary visits, regularly check the following:
✔ Every 2 weeks to 1 month:
- Creatinine, BUN, Phosphorus
- Electrolytes, Bicarbonate (HCO₃⁻): assess for acidosis
- HCT/RBC: check for anemia
✔ Every 3 months:
- Blood pressure (monitor for hypertension)
- proBNP (a biomarker indicating cardiac stress)
- Chest X-ray or auscultation (check for pulmonary edema or cardiac abnormalities)
Emergency Symptom Checklist
If your cat shows any of the following signs, seek veterinary care immediately:
- Complete loss of appetite
- Vomiting more than 3 times a day
- Extreme lethargy or unsteady gait
- Open-mouth breathing or difficulty breathing
- No bowel movement for over 48 hours
- Persistent straining to urinate or defecate every 5 minutes
When to Consider Changing Clinics
If your current veterinary clinic responds in the following ways during Stage 3, it may be time to seek a second opinion:
- Does not offer or prescribe subcutaneous fluids
- Fails to explain or address metabolic acidosis (low HCO₃⁻)
- States “there’s nothing more we can do” without attempting combination treatment
Summary – Stage 3 Care
✔ Supplement Protocol
- AIM + AMPK + Probiotics + Omega-3 + Melatonin
✔ Diet
- Feed renal prescription diet; initiate assisted feeding if needed
✔ Subcutaneous Fluids
- Daily Sub-Q fluids under veterinary supervision
Complete Your Cat Care Routine
Before & After on the Greycoat Program
Our mission is to stop feline kidney disease
— Greycoat Research