Managing CKD and HCM Together in Cats
As cats move beyond mid-stage CKD Stage 2 into Stage 3, blood pressure often rises and the heart begins to feel the strain. Over time, this pressure can cause the heart walls to thicken, leading to hypertrophy (HCM).
For cats receiving subcutaneous fluids, rapid shifts in fluid volume can place additional stress on the kidneys. These cats require careful management and targeted nutrients to help reduce strain and support stability.
At Greycoat Research, we have provided consultation and care in over 300 cases where CKD has progressed into heart complications. From these experiences, we have learned that small adjustments in diet, supplements, and daily routines can bring meaningful improvements in both stability and quality of life.
Why Protein Balance Matters
One of the most important factors in managing both CKD and HCM is protein balance. While protein restriction is often recommended for kidney care, excessive restriction can weaken the heart muscle and make hypertrophy worse.
In the U.S., some hospitals have reported encouraging results using rapamycin for cats with HCM, but this treatment is not always accessible. Where rapamycin is unavailable, natural compounds such as berberine, pterostilbene, and melatonin may help indirectly slow progression.
Rapamycin works mainly through mTOR inhibition, while compounds like berberine, quercetin, and resveratrol activate AMPK, providing indirect support through the same pathway.
The Right Mix of Heart Nutrients
Nutrients play an essential role in strengthening cardiac function, but balance is key.
- Essential for the heart: Taurine, CoQ10, ubiquinol, carnitine
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To balance with: Berberine, pterostilbene, melatonin
This combination helps provide energy to the heart while avoiding unnecessary strain.
Rest as Recovery
Quality sleep is vital for the recovery of both heart and kidney cells. When cells are able to rest, they maintain energy balance, reduce stress, and support renewal.
This is why Greycoat Research developed Greycoat Calm, a supplement designed for cats with CKD and HCM. With berberine, pterostilbene, and melatonin as its key actives, it supports cellular rest and can be a valuable part of care for cats in mid-Stage 2 CKD, Stage 3, or those experiencing heart strain. Just one capsule in the evening can become a simple nightly routine to support deeper rest and stability.
Always by Your Side
At Greycoat Research, we remain committed to supporting every guardian caring for a cat with CKD or HCM. With the right knowledge and tools, small daily choices can build a foundation of stability and comfort.
Thank you for trusting us to be part of your journey. We are here with you and your beloved cat, every step of the way.
